Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714047 | 0.93 | MRGPRX4 (0.51) | MRGPRX4PLAUSMPD1NR4A2GPR34 | |
| SCHEMBL7662548 | 0.91 | MRGPRX4 (0.51) | MRGPRX4PLAUSMPD1NR4A2GPR34 | |
| SCHEMBL7665912 | 0.86 | MRGPRX4 (0.48) | MRGPRX4PLAUSMPD1GPR34FFAR1 | |
| SCHEMBL7662745 | 0.84 | MRGPRX4 (0.46) | MRGPRX4PLAUSMPD1GPR34EGLN1 | |
| SCHEMBL7670815 | 0.84 | MRGPRX4 (0.47) | MRGPRX4PLAUMAOBFFAR1FFAR4 | |
| SCHEMBL7658946 | 0.84 | MRGPRX4 (0.51) | MRGPRX4PLAUGPR34MAOBFFAR1 | |
| SCHEMBL7668085 | 0.84 | F2 (0.58) | MRGPRX4PLAUNR4A2F2 | |
| SCHEMBL6753784 | 0.82 | LOXL2 (0.53) | MRGPRX4PLAUEGLN1 | |
| SCHEMBL7670999 | 0.82 | MRGPRX4 (0.46) | MRGPRX4PLAUSMPD1NR4A2GPR34 | |
| SCHEMBL7664318 | 0.82 | MRGPRX4 (0.52) | MRGPRX4PLAUPRKDCATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |