Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668685 | 0.90 | MRGPRX4 (0.45) | MRGPRX4PLAUMMP13 | |
| SCHEMBL7714047 | 0.89 | MRGPRX4 (0.51) | MRGPRX4FFAR1PLAUNR1H4FFAR4 | |
| SCHEMBL7662548 | 0.89 | MRGPRX4 (0.51) | MRGPRX4FFAR1PLAUNR1H4FFAR4 | |
| SCHEMBL7665912 | 0.88 | MRGPRX4 (0.48) | MRGPRX4FFAR1PLAUADAMTS4MMP13 | |
| SCHEMBL7670815 | 0.86 | MRGPRX4 (0.47) | MRGPRX4FFAR1PLAUMAOBFFAR4 | |
| SCHEMBL7662745 | 0.84 | MRGPRX4 (0.46) | MRGPRX4FFAR1PLAUFFAR4GPR34 | |
| SCHEMBL7665464 | 0.84 | MRGPRX4 (0.54) | MRGPRX4RXRARXRBNR1H4ADAMTS4 | |
| SCHEMBL7660874 | 0.84 | MRGPRX4 (0.47) | MRGPRX4FFAR1PLAUMAOBFFAR4 | |
| SCHEMBL6751413 | 0.81 | PLAU (0.47) | MRGPRX4PLAUMMP13 | |
| SCHEMBL7663246 | 0.80 | MRGPRX4 (0.48) | MRGPRX4PLAUGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |