Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662548 | 0.96 | MRGPRX4 (0.51) | MRGPRX4PLAUSMPD1GPR34NR4A2 | |
| SCHEMBL7660874 | 0.93 | MRGPRX4 (0.47) | MRGPRX4PLAUSMPD1GPR34NR4A2 | |
| SCHEMBL7665912 | 0.90 | MRGPRX4 (0.48) | MRGPRX4PLAUSMPD1GPR34FFAR1 | |
| SCHEMBL7662745 | 0.89 | MRGPRX4 (0.46) | MRGPRX4PLAUSMPD1GPR34EGLN1 | |
| SCHEMBL7658946 | 0.89 | MRGPRX4 (0.51) | MRGPRX4PLAUGPR34FFAR1FFAR4 | |
| SCHEMBL7670815 | 0.89 | MRGPRX4 (0.47) | MRGPRX4PLAUFFAR1FFAR4GAA | |
| SCHEMBL7670999 | 0.86 | MRGPRX4 (0.46) | MRGPRX4PLAUSMPD1GPR34NR4A2 | |
| SCHEMBL6751413 | 0.85 | PLAU (0.47) | MRGPRX4PLAUEGLN1KAT6A | |
| SCHEMBL7661462 | 0.85 | RAB9A (0.46) | MRGPRX4PLAUSMPD1GPR34NR4A2 | |
| SCHEMBL7663246 | 0.84 | MRGPRX4 (0.48) | MRGPRX4PLAUGPR34GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380430-B1 | ANTICOAGULANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTERHAFTUNG (DE) | 2002-04-30 | — | — | US | disclosed |