SCHEMBL766096

SCHEMBL766096

C=Cc1ccc(N(c2cccc(C)c2)c2c(C)cc(-c3cc(C)c(N(c4cccc(C)c4)c4cccc(C)c4)c(C)c3)cc2C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EGFR P00533 2/20 0.32
CSF1R P07333 2/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14076735 0.91 TP53 (0.32) TP53TDP1HSD17B1HSD17B2
SCHEMBL12954835 0.87 TP53 (0.39) TP53TDP1EGFRCSF1RHSD17B1
SCHEMBL766111 0.85 TP53 (0.35) TP53TDP1EGFRCSF1RHSD17B1
SCHEMBL12018951 0.84 TP53 (0.37) TP53TDP1EGFRCSF1RHSD17B1
SCHEMBL13770596 0.84 TP53 (0.39) TP53TDP1EGFRCSF1RACHE
SCHEMBL13425322 0.83 ACHE (0.44) TP53TDP1EGFRCSF1RHSD17B1
SCHEMBL12858349 0.82 HSD17B1 (0.34) TP53TDP1HSD17B1HSD17B2
SCHEMBL12954832 0.82 TP53 (0.33) TP53TDP1HSD17B1HSD17B2
SCHEMBL13589319 0.78 ACHE (0.39) TP53TDP1EGFRCSF1RHSD17B1
SCHEMBL8354975 0.78 S100B (0.31) TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735875-B2 Light emitting element, method for manufacturing light emitting element, image display device, and illuminating device SHOWA DENKO K.K. (JP) 2014-05-27 US disclosed
US-8735875-B2 Light emitting element, method for manufacturing light emitting element, image display device, and illuminating device SHOWA DENKO K.K. (JP) 2014-05-27 US disclosed
US-8441003-B2 Phosphorescent polymer compound based on iridium polymer complex and organic electroluminescent device utilizing the same SHOWA DENKO K.K. (JP) 2013-05-14 US disclosed
US-8441003-B2 Phosphorescent polymer compound based on iridium polymer complex and organic electroluminescent device utilizing the same SHOWA DENKO K.K. (JP) 2013-05-14 US disclosed
US-8426038-B2 Phosphorescent polymer compound and organic electroluminescence device using the same SHOWA DENKO K.K. (JP) 2013-04-23 US disclosed
US-8426038-B2 Phosphorescent polymer compound and organic electroluminescence device using the same SHOWA DENKO K.K. (JP) 2013-04-23 US disclosed
US-20120267614-A1 LIGHT EMITTING ELEMENT, METHOD FOR MANUFACTURING LIGHT EMITTING ELEMENT, IMAGE DISPLAY DEVICE, AND ILLUMINATING DEVICE SHOWA DENKO K.K. (JP) 2012-10-25 US disclosed
US-20120267614-A1 LIGHT EMITTING ELEMENT, METHOD FOR MANUFACTURING LIGHT EMITTING ELEMENT, IMAGE DISPLAY DEVICE, AND ILLUMINATING DEVICE SHOWA DENKO K.K. (JP) 2012-10-25 US disclosed
US-20120256171-A1 PHOSPHINE OXIDE COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, PRODUCTION METHOD AND USES THEREOF SHOWA DENKO K.K. (JP) 2012-10-11 US disclosed
US-20120256536-A1 PHOSPHINE OXIDE COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, PRODUCTION METHOD AND USES THEREOF SHOWA DENKO K.K. (JP) 2012-10-11 US disclosed
US-20090091918-A1 ORGANIC ELECTRO-LUMINESCENCE ELEMENT, PRODUCTION METHOD AND USE THEREOF SHOWA DENKO K.K. (JP) 2009-04-09 US disclosed
US-20090058286-A1 ORGANIC LIGHT-EMITTING DEVICE USING A COMPOUND HAVING A CARRIER TRANSPORT PROPERTY AND A PHOSPHORESCENT PROPERTY SHOWA DENKO K.K (JP) 2009-03-05 US disclosed
US-20090058286-A1 ORGANIC LIGHT-EMITTING DEVICE USING A COMPOUND HAVING A CARRIER TRANSPORT PROPERTY AND A PHOSPHORESCENT PROPERTY SHOWA DENKO K.K (JP) 2009-03-05 US disclosed
US-20080050604-A1 Polymer Light-Emitting Material and Organic Light Emitting Element SHOWA DENKO K.K. (JP) 2008-02-28 US disclosed
US-20080050604-A1 Polymer Light-Emitting Material and Organic Light Emitting Element SHOWA DENKO K.K. (JP) 2008-02-28 US disclosed
WO-2007129776-A1 DISPLAY DEVICE AND METHOD OF PRODUCING THE SAME SHOWA DENKO K.K. (JP) 2007-11-15 WO disclosed
WO-2007119629-A1 AN ORGANIC LIGHT-EMITTING DEVICE USING A COMPOUND HAVING A CARRIER TRANSPORT PROPERTY AND A PHOSPHORESCENT PROPERTY SHOWA DENKO K.K. (JP) 2007-10-25 WO disclosed
WO-2007026726-A2 3D DISPLAY DEVICE AND 3D DISPLAY METHOD SHOWA DENKO K.K. (JP) 2007-03-08 WO disclosed
WO-2007024007-A1 ORGANIC ELECTRO-LUMINESCENCE ELEMENT, PRODUCTION METHOD AND USE THEREOF SHOWA DENKO K.K. (JP) 2007-03-01 WO disclosed
WO-2007020881-A1 ORGANIC ELECTROLUMINESCENCE DEVICE USING A COPOLYMER AND A PHOSPHORESCENT COMPOUND SHOWA DENKO K.K. (JP) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120256171-A1 PHOSPHINE OXIDE COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, PRODUCTION METHOD AND USES THEREOF SLCO4C1, SLCO2A1, SLCO2B1 TP53 3826/4885TDP1 3102/4885EGFR 118/4885
US-20120256536-A1 PHOSPHINE OXIDE COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, PRODUCTION METHOD AND USES THEREOF SLCO4C1, SLCO2A1, SLCO2B1 TP53 3826/4885TDP1 3102/4885EGFR 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.