SCHEMBL766141

SCHEMBL766141

C#CCOCCCCCCCCCCCCO

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
GAA P10253 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548512 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL11528188 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL29118750 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL2723206 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL9762896 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL15445144 1.00 TSHR (0.52) TSHRGAAMEN1KMT2ATHRB
SCHEMBL2360071 0.98
SCHEMBL1142610 0.90
SCHEMBL2706386 0.90 MEN1 (0.53) TSHRMEN1KMT2ATHRBHTT
SCHEMBL766061 0.87 TSHR (0.56) TSHRMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633409-B2 Bola-amphiphilic compounds and their uses for biomedical applications Universite de Bordeaux (FR) 2020-04-28 US disclosed
US-20190233460-A1 Bola-amphiphilic compounds and their uses for biomedical applications Universite de Bordeaux (FR) 2019-08-01 US disclosed
US-10227372-B2 Bola-amphiphilic compounds and their uses for biomedical applications Universite de Bordeaux (FR) 2019-03-12 US disclosed
US-20170240583-A1 Bola-amphiphilic compounds and their uses for biomedical applications Universite de Bordeaux (FR) 2017-08-24 US disclosed
US-9533049-B2 Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof UNIVERSITE D'AIX-MARSEILLE (FR) 2017-01-03 US disclosed
US-9533049-B2 Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof UNIVERSITE D'AIX-MARSEILLE (FR) 2017-01-03 US disclosed
WO-2016055493-A1 BOLA-AMPHIPHILIC COMPOUNDS AND THEIR USES FOR BIOMEDICAL APPLICATIONS Universite de Bordeaux (FR) 2016-04-14 WO disclosed
EP-3006452-A1 Bola-amphiphilic compounds and their uses for biomedical applications UNIVERSITE DE BORDEAUX (FR) 2016-04-13 EP disclosed
EP-2435031-B1 Functional amphiphilic molecule or macromolecule formulations with multiple compartments UNIV BORDEAUX (FR) 2015-09-16 EP disclosed
US-9050268-B2 Functional amphipilic molecule or macromolecule formulations with multiple compartments UNIVERSITE D'AIX-MARSEILLE (FR) 2015-06-09 US disclosed
US-20120070505-A1 FUNCTIONAL AMPHIPILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE DE LA MEDITERRANEE (FR) 2012-03-22 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
WO-2010136676-A1 FUNCTIONAL AMPHIPHILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2010-12-02 WO disclosed
WO-2010136676-A1 FUNCTIONAL AMPHIPHILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2010-12-02 WO disclosed
EP-2231132-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF Université Victor Segalen Bordeaux 2 (FR) 2010-09-29 EP disclosed
WO-2009098404-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEEUX 2 (FR) 2009-08-13 WO disclosed
WO-2009098404-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEEUX 2 (FR) 2009-08-13 WO disclosed
US-4162328-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1979-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10633409-B2 Bola-amphiphilic compounds and their uses for biomedical applications BOLA2; BOLA2B, ANXA1, LIPG TSHR 4267/4885GAA 946/4885MEN1 1590/4885
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof CETP, PCTP, ABCB4 TSHR 3974/4885GAA 352/4885MEN1 1475/4885
US-20120070505-A1 FUNCTIONAL AMPHIPILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS ANXA2, SLC47A2, ABCB4 TSHR 3691/4885GAA 471/4885MEN1 1561/4885
US-20170240583-A1 Bola-amphiphilic compounds and their uses for biomedical applications BOLA2; BOLA2B, ANXA1, LIPG TSHR 4267/4885GAA 946/4885MEN1 1590/4885
US-10227372-B2 Bola-amphiphilic compounds and their uses for biomedical applications BOLA2; BOLA2B, ANXA1, LIPG TSHR 4267/4885GAA 946/4885MEN1 1590/4885
US-20190233460-A1 Bola-amphiphilic compounds and their uses for biomedical applications BOLA2; BOLA2B, ANXA1, LIPG TSHR 4267/4885GAA 946/4885MEN1 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.