Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539697 | 0.76 | L3MBTL1 (0.79) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19090370 | 0.74 | TDP1 (0.73) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30008478 | 0.72 | L3MBTL1 (0.91) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4113524 | 0.72 | RAB9A (0.72) | L3MBTL1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5032454 | 0.72 | L3MBTL1 (0.72) | L3MBTL1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1431137 | 0.72 | PTK2 (1.00) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4687835 | 0.71 | NPSR1 (0.65) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29538166 | 0.71 | NPSR1 (0.65) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24654650 | 0.71 | L3MBTL1 (0.78) | L3MBTL1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL18286136 | 0.71 | TDP1 (0.73) | L3MBTL1RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376492-B1 | GUANIDINE DERIVATIVES | MEDIVIR AB (SE) | 2002-04-23 | — | — | US | disclosed |