Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GCLC | P48506 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222803 | 0.77 | LAP3 (0.41) | LAP3GCLCGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2850492 | 0.75 | LAP3 (0.54) | LAP3 | |
| SCHEMBL6227459 | 0.75 | LAP3 (0.54) | LAP3 | |
| Isoleucine SCHEMBL31276087 | 0.74 | SLC7A5 (0.46) | LAP3SLC7A5GCLC | |
| SCHEMBL28015797 | 0.74 | GSR (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Isoleucine SCHEMBL1614385 | 0.74 | SLC7A5 (0.46) | LAP3SLC7A5GCLCGRIN2DGRIN3B | |
| Medronic Acid SCHEMBL1614267 | 0.71 | SLC7A5 (0.68) | LAP3SLC7A5GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8634272 | 0.71 | TDP1 (0.50) | LAP3 | |
| Phosphoric Acid SCHEMBL31115554 | 0.70 | GCLC (0.53) | LAP3SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL8973660 | 0.70 | SLC7A5 (0.52) | LAP3SLC1A3SLC1A2SLC1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362009-B1 | CAPTURING A SUBSTRATE ON SOLID SUPPORT AND ACTIVATINGSUBSTRATE TO REACT WITH REAGENT WITH WHICH UNACTIVATED SUBSTRATE DOES NOT REACT; REACTING ACTIVATED SUBSTRATE ON SOLID PHASE WITH REAGENT TO GIVE AN ADDITION PRODUCT | MERCK & CO., INC. | 2002-03-26 | — | — | US | disclosed |