Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257640 | 0.83 | NPC1 (0.87) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL8066866 | 0.82 | ABCG2 (0.67) | MAPTLMNAKMT2AMEN1ABCG2 | |
| SCHEMBL18099393 | 0.78 | MEN1 (0.74) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL28549138 | 0.78 | ABCG2 (0.71) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL9717780 | 0.78 | MEN1 (0.74) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7186177 | 0.78 | ABCG2 (0.72) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL7186174 | 0.78 | ABCG2 (0.72) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL7656609 | 0.77 | MAPT (0.74) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL7656614 | 0.77 | MAPT (0.74) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL31233074 | 0.77 | MAPT (0.74) | RAB9ANPC1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |