Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.87 |
| ▸ | RAB9A | P51151 | 4/20 | 0.87 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717780 | 0.83 | MEN1 (0.74) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL18099393 | 0.83 | MEN1 (0.74) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL7662803 | 0.83 | RAB9A (0.61) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL28263081 | 0.83 | RELA (0.73) | NPC1RAB9AALDH1A1LMNAALOX5 | |
| SCHEMBL25299890 | 0.81 | MAPT (1.00) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL28263080 | 0.81 | SNCA (0.71) | NPC1RAB9AALDH1A1LMNAALOX5 | |
| SCHEMBL6357635 | 0.79 | ALOX5 (0.78) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL31676388 | 0.79 | ALOX5 (0.78) | NPC1RAB9AALDH1A1LMNAALOX5 | |
| SCHEMBL6357636 | 0.79 | ALOX5 (0.78) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL28549138 | 0.79 | ABCG2 (0.71) | NPC1RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |