Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662940 | 1.00 | LMNA (0.43) | LMNAMAPTHTTSMN1; SMN2NPC1 | |
| SCHEMBL7661046 | 0.85 | RXFP1 (0.49) | LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7661053 | 0.85 | RXFP1 (0.49) | LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10387140 | 0.82 | PPARG (0.47) | LMNAMAPTNPC1RAB9AKMT2A | |
| SCHEMBL10387139 | 0.82 | PPARG (0.47) | LMNAMAPTNPC1RAB9AKMT2A | |
| SCHEMBL7662861 | 0.82 | ALDH1A1 (0.41) | LMNASMN1; SMN2ALDH1A1HIF1ATDP1 | |
| SCHEMBL7662857 | 0.82 | ALDH1A1 (0.41) | LMNASMN1; SMN2ALDH1A1HIF1ATDP1 | |
| SCHEMBL9262554 | 0.80 | HIF1A (0.50) | SMN1; SMN2ALDH1A1HIF1ATDP1 | |
| SCHEMBL7172810 | 0.80 | HIF1A (0.50) | SMN1; SMN2ALDH1A1HIF1ATDP1 | |
| SCHEMBL7172808 | 0.80 | HIF1A (0.50) | SMN1; SMN2ALDH1A1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| US-5585513-A | CHEMICAL INTERMEDIATES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |