Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068934 | 0.91 | SIGMAR1 (0.51) | KMT2AMAPK1SMN1; SMN2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL8077076 | 0.87 | KMT2A (0.52) | KMT2AALDH1A1MAPK1SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL8077073 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1MAPK1SMN1; SMN2PKM | |
| SCHEMBL7662978 | 0.81 | SMN1; SMN2 (0.72) | KMT2AALDH1A1SMN1; SMN2PKMPOLB | |
| SCHEMBL8444778 | 0.79 | SLC9A1 (0.50) | KMT2AMEN1 | |
| SCHEMBL8444776 | 0.78 | SIGMAR1 (0.46) | KMT2AALDH1A1SMN1; SMN2POLBNPSR1 | |
| Hydrochloric Acid SCHEMBL8068489 | 0.78 | SLC9A1 (0.49) | KMT2AMEN1 | |
| SCHEMBL8068849 | 0.78 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPK1SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL8068487 | 0.78 | SIGMAR1 (0.45) | KMT2AALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL8068480 | 0.76 | CYP19A1 (0.55) | KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |