SCHEMBL7663262

SCHEMBL7663262

NC(CC(=O)OCCCc1ccccc1)CS(=O)(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MMP2 P08253 4/20 0.44
MMP9 P14780 4/20 0.44
MMP8 P22894 4/20 0.44
MMP1 P03956 3/20 0.44
MMP3 P08254 3/20 0.44
TDP1 Q9NUW8 1/20 0.43
NPC1 O15118 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
CTDSP1 Q9GZU7 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
APOBEC3A P31941 2/20 0.42
APOBEC3G Q9HC16 2/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7674078 0.83 LMNA (0.42) LMNAALDH1A1
SCHEMBL7667735 0.80 CYP1A2 (0.36) SMN1; SMN2ALDH1A1TDP1NPC1RECQL
SCHEMBL27579710 0.75 LMNA (0.60) LMNASMN1; SMN2ALDH1A1MMP2MMP1
SCHEMBL7345314 0.75 HSD11B1 (0.46) MMP2MAPT
SCHEMBL7667208 0.74 ALDH1A1 (0.58) LMNASMN1; SMN2ALDH1A1MMP2MMP9
SCHEMBL872830 0.74 LMNA (0.58) LMNASMN1; SMN2ALDH1A1MMP2MMP1
SCHEMBL7746226 0.74 HSD11B1 (0.44) ALDH1A1NPC1RECQLRAB9A
SCHEMBL27358460 0.73 ALDH1A1 (0.47) ALDH1A1MMP2MMP9MMP8MMP1
SCHEMBL8423546 0.73 LMNA (0.48) LMNASMN1; SMN2ALDH1A1TDP1NPC1
SCHEMBL27536255 0.73 LMNA (0.57) LMNASMN1; SMN2ALDH1A1TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US claimed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP claimed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO claimed
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US disclosed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP disclosed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO disclosed