SCHEMBL7663449

SCHEMBL7663449

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 2/20 0.48
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTGS2 P35354 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HIF1A Q16665 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
MAOB P27338 4/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 1/20 0.46
MAOA P21397 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729093 0.99 GSTP1 (0.47) GSTP1LMNACYP1A2PTGS1SLC6A2
SCHEMBL8726167 0.99 GSTP1 (0.47) GSTP1LMNACYP1A2PTGS1SLC6A2
SCHEMBL669799 0.91 LMNA (0.53) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5406101 0.84 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL6059708 0.83 LMNA (0.51) GSTP1LMNACYP1A2PTGS1SLC6A2
SCHEMBL6060406 0.83 LMNA (0.51) GSTP1LMNACYP1A2PTGS1SLC6A2
SCHEMBL28028225 0.79 LMNA (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL197017 0.79 LMNA (0.72) GSTP1LMNACYP1A2PTGS1SLC6A2
SCHEMBL255002 0.77 MAOB (0.69) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27416065 0.77 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6388146-B1 AROMATIC UNSATURATED NOMONER SHARP KABUSHIKI KAISHA (JP) 2002-05-14 US disclosed
US-5814378-A ACRYLATED ESTER OF A BIPHENYL COMPOUND SHARP KABUSHIKI KAISHA (JP) 1998-09-29 US disclosed