Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.45 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401753 | 0.86 | PRKCI (0.47) | PRKCIKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL23015823 | 0.86 | PRKCI (0.61) | PRKCIKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL11614989 | 0.85 | PRKCI (0.49) | PRKCIKDM4ERAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10889082 | 0.83 | KMT2A (0.46) | PRKCIKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL9687654 | 0.81 | PRKCI (0.43) | PRKCIKDM4ERAB9AMEN1KMT2A | |
| SCHEMBL24814072 | 0.80 | MEN1 (0.48) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL197857 | 0.78 | KDM5A (0.54) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL3402923 | 0.77 | ALDH1A1 (0.44) | PRKCIKDM4ERAB9AALDH1A1CYP1A2 | |
| SCHEMBL13165570 | 0.77 | TYK2 (0.66) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL14168412 | 0.77 | ALDH1A1 (0.52) | KDM4ERAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |