Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424577 | 0.77 | TSHR (0.48) | MAOBMAOAANPEPCYP1A2KDM4E | |
| SCHEMBL1783171 | 0.77 | MAOB (0.43) | MAOBMAOAANPEPCYP1A2KDM4E | |
| SCHEMBL1782335 | 0.74 | MAOB (0.41) | MAOBMAOAANPEPCYP1A2KDM4E | |
| SCHEMBL19746 | 0.74 | CYP19A1 (0.45) | MAOBMAOAANPEPKDM4EADORA3 | |
| SCHEMBL30292163 | 0.73 | SMN1; SMN2 (0.42) | MAOBMAOAANPEPKDM4EADORA3 | |
| SCHEMBL8823819 | 0.73 | MAOB (0.39) | MAOBMAOAANPEPCYP1A2KDM4E | |
| SCHEMBL5328708 | 0.73 | SMN1; SMN2 (0.42) | MAOBMAOAANPEPKDM4EADORA3 | |
| SCHEMBL8496949 | 0.73 | MAOB (0.39) | MAOBMAOAANPEPCYP1A2KDM4E | |
| SCHEMBL11733122 | 0.73 | CYP19A1 (0.44) | MAOBMAOAANPEPKDM4EADORA3 | |
| SCHEMBL20525259 | 0.72 | MAOA (0.38) | MAOBMAOAANPEPNISCHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388081-B1 | 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries | LION BIOSCIENCE AG (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6262269-B1 | 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries | TREGA BIOSCIENCES, INC. | 2001-07-17 | — | — | US | disclosed |