Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 5/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292163 | 0.85 | SMN1; SMN2 (0.42) | MAOAMAOBTSHRHPGDANPEP | |
| SCHEMBL5328708 | 0.85 | SMN1; SMN2 (0.42) | MAOAMAOBTSHRHPGDANPEP | |
| SCHEMBL20525260 | 0.80 | HDAC3 (0.36) | MAOAMAOBTSHRHPGDANPEP | |
| Acetic Acid SCHEMBL11666716 | 0.76 | KMT2A (0.43) | MAOBGABRA1GABRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2424577 | 0.75 | TSHR (0.48) | MAOAMAOBTSHRANPEPNISCH | |
| SCHEMBL1783171 | 0.75 | MAOB (0.43) | MAOAMAOBTSHRHPGDANPEP | |
| SCHEMBL7664111 | 0.72 | MAOB (0.43) | MAOAMAOBTSHRHPGDANPEP | |
| SCHEMBL8823819 | 0.71 | MAOB (0.39) | MAOAMAOBGABRA1GABRB2TSHR | |
| SCHEMBL8496949 | 0.71 | MAOB (0.39) | MAOAMAOBTSHRHPGDANPEP | |
| SCHEMBL28229403 | 0.71 | MAOA (0.39) | MAOAMAOBTSHRHPGDANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093667-B1 | Coumarinyl-thiazole-sulfonyl conjugate and preparation thereof | COMSATS INSTITUTE OF INFORMATION TECHNOLOGY (PK) | 2018-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093667-B1 | Coumarinyl-thiazole-sulfonyl conjugate and preparation thereof | OPRK1, OPRL1, OGFR | MAOA 418/4885MAOB 520/4885GABRA1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.