Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.42 |
| ▸ | ITGAV | P06756 | 17/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673640 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL7668760 | 0.77 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL7664091 | 0.77 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL7672674 | 0.75 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7361297 | 0.75 | ITGB3 (0.54) | ITGB3ITGAVITGA2B | |
| SCHEMBL7663613 | 0.75 | ITGB3 (0.37) | ITGB3ITGAVITGA2BDGAT1KCNH2 | |
| SCHEMBL7360585 | 0.75 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL8328325 | 0.74 | ITGB3 (0.40) | ITGB3ITGAVITGA2BDGAT1KCNH2 | |
| SCHEMBL8328924 | 0.70 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL8525562 | 0.70 | ITGB3 (0.39) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495545-B1 | ANTIOSTEOPOROTIC, ANTIRESTENOTIC, ANTICARCINOGENIC AND ANTIATHEROSCLEROTIC ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| US-6339083-B1 | FOR THERAPY OF OSTEOPOROSIS, RESTENOSIS, CARCINOSES AND/OR ARTERIOSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-15 | — | — | US | disclosed |