Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGAV | P06756 | 11/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330616 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL8328924 | 0.77 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL8467659 | 0.76 | GABRG2 (0.39) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7366878 | 0.75 | ITGB3 (0.38) | ITGB3ITGAVITGA2BHPGD | |
| SCHEMBL7664124 | 0.74 | ITGB3 (0.42) | ITGB3ITGAVITGA2BDGAT1KCNH2 | |
| SCHEMBL8468002 | 0.71 | DHODH (0.37) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL8323234 | 0.71 | KLK7 (0.36) | ITGB3ITGA2B | |
| SCHEMBL8467321 | 0.70 | GABRA1 (0.35) | MEN1KMT2A | |
| SCHEMBL7668760 | 0.68 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL7672674 | 0.66 | ITGB3 (0.57) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |