Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661640 | 0.90 | F2 (0.44) | F2MRGPRX4F10PRSS1PRSS2 | |
| SCHEMBL7665750 | 0.80 | MRGPRX4 (0.47) | F2MRGPRX4 | |
| SCHEMBL7670816 | 0.80 | F10 (0.67) | F2MRGPRX4F10PRSS1PRSS2 | |
| SCHEMBL7454069 | 0.80 | F2 (0.70) | F2MRGPRX4F10PRSS1NR4A2 | |
| SCHEMBL8072969 | 0.79 | F2 (0.54) | F2MRGPRX4F10NR4A2 | |
| SCHEMBL7669668 | 0.76 | MRGPRX4 (0.65) | F2MRGPRX4F10NR4A2 | |
| SCHEMBL7660470 | 0.75 | F2 (0.63) | F2MRGPRX4F10NR4A2 | |
| SCHEMBL7660455 | 0.73 | F2 (0.46) | F2MRGPRX4F10PRSS1 | |
| SCHEMBL7663227 | 0.73 | PPIA (0.46) | F2MRGPRX4F10PRSS1 | |
| SCHEMBL7664103 | 0.72 | F10 (0.62) | F2MRGPRX4F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |