Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659126 | 0.85 | MRGPRX4 (0.49) | PPIANPC1RAB9ALTA4HMAPK14 | |
| SCHEMBL7661640 | 0.83 | F2 (0.44) | F2NPC1RAB9ASMN1; SMN2DHFR | |
| SCHEMBL7660455 | 0.82 | F2 (0.46) | F2MRGPRX1MRGPRX4F10PRSS1 | |
| SCHEMBL7719048 | 0.82 | F2 (0.66) | F2MRGPRX4F10PRSS1 | |
| SCHEMBL7664103 | 0.81 | F10 (0.62) | F2MRGPRX4F10PRSS1 | |
| SCHEMBL7668085 | 0.81 | F2 (0.58) | F2MRGPRX4F10 | |
| SCHEMBL7663161 | 0.80 | MRGPRX4 (0.42) | F2NPC1RAB9ASMN1; SMN2DHFR | |
| SCHEMBL7658103 | 0.79 | F2 (0.53) | F2NPC1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL7659032 | 0.78 | PRSS1 (0.49) | F2MRGPRX1F10PRSS1 | |
| SCHEMBL7664269 | 0.78 | F2 (0.60) | F2MRGPRX4F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |