Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 3/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665988 | 0.94 | ALDH1A1 (0.52) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7665999 | 0.86 | CHRNA1 (0.53) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7654949 | 0.86 | CHRNA1 (0.54) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL6323463 | 0.83 | CHRNA7 (0.56) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL6323459 | 0.83 | CHRNA7 (0.56) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7665043 | 0.80 | SMN1; SMN2 (0.50) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7665049 | 0.80 | SMN1; SMN2 (0.50) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL7638837 | 0.80 | CHRNA1 (0.66) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL676764 | 0.80 | CHRNA1 (0.66) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8113019 | 0.80 | CHRNA1 (0.66) | CHRNA1CHRNA7CHRNA3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465492-B1 | SUCH AS 2-((4-METHYLPHENYL)SULFONYLIMINO) IMIDAZOLIDINE; PESTICIDES; KILLING INSECTS ON PLANTS | SINON CORPORATION (TW) | 2002-10-15 | — | — | US | disclosed |