Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.66 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676764 | 1.00 | CHRNA1 (0.66) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7638837 | 1.00 | CHRNA1 (0.66) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL12002532 | 0.94 | ALDH1A1 (0.64) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL237917 | 0.94 | ALDH1A1 (0.64) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL22278 | 0.94 | ALDH1A1 (0.64) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL29436142 | 0.94 | ALDH1A1 (0.64) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL182289 | 0.94 | ALDH1A1 (0.64) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL9045947 | 0.90 | ALDH1A1 (0.59) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL6642346 | 0.89 | CHRNA1 (0.55) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 | |
| Imidacloprid SCHEMBL15284816 | 0.89 | ALDH1A1 (0.61) | CHRNA1CHRNA3CHRNA7ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685477-B1 | Insecticidal tetrahydrofuran-compound | MITSUI CHEMICALS INC (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-0685477-A1 | Insecticidal tetrahydrofuran-compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-12-06 | — | — | EP | disclosed |