Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323463 | 1.00 | CHRNA7 (0.56) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7664381 | 0.83 | CHRNA1 (0.54) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5833743 | 0.83 | CHRNA7 (0.58) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8113019 | 0.81 | CHRNA1 (0.66) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7638837 | 0.81 | CHRNA1 (0.66) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL676764 | 0.81 | CHRNA1 (0.66) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7654949 | 0.81 | CHRNA1 (0.54) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7496995 | 0.79 | CHRNA1 (0.63) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9889724 | 0.79 | ALDH1A1 (0.54) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL22268364 | 0.79 | ALDH1A1 (0.57) | CHRNA7CHRNA1CHRNA3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | claimed |
| US-6900202-B2 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1218371-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001070733-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | CHRNA2, CHRNA7, CHRNB2 | CHRNA7 2/4885CHRNA1 6/4885CHRNA3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.