Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 19/20 | 0.53 |
| ▸ | DRD2 | P14416 | 18/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187139 | 0.91 | DRD2 (0.51) | DRD4DRD2MEN1ADRA1DADRA1A | |
| SCHEMBL8194860 | 0.76 | GAA (0.56) | MEN1KMT2A | |
| Water SCHEMBL8200223 | 0.75 | GAA (0.55) | MEN1KMT2A | |
| SCHEMBL7686692 | 0.73 | DRD4 (0.53) | DRD4DRD2MEN1ADRA1DADRA1A | |
| SCHEMBL27571236 | 0.69 | GAA (0.61) | — | |
| SCHEMBL7549710 | 0.67 | DRD4 (0.56) | DRD4DRD2MEN1KMT2A | |
| SCHEMBL9868436 | 0.67 | GAA (0.58) | DRD2 | |
| SCHEMBL28263579 | 0.67 | GAA (0.62) | MEN1KMT2A | |
| SCHEMBL8187174 | 0.67 | DRD2 (0.71) | DRD4DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL29569853 | 0.66 | GAA (0.65) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355644-B1 | NERVOUS SYSTEM DISORDERS AND TREATMENT OF SCHIZOPHRENIA AND BIPOLAR DISORDER | NEUROGEN CORPORATION | 2002-03-12 | — | — | US | disclosed |
| WO-2000076967-A1 | BENZYLPIPERAZINYL-INDOLINYLETHANONES | NEUROGEN CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |