Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056925 | 0.88 | ALDH1A1 (0.33) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7705910 | 0.82 | CA2 (0.32) | TSHR | |
| SCHEMBL7622153 | 0.81 | SORD (0.32) | — | |
| SCHEMBL4384751 | 0.79 | SORD (0.30) | — | |
| SCHEMBL4388950 | 0.78 | — | — | |
| SCHEMBL4376123 | 0.77 | — | — | |
| SCHEMBL7194100 | 0.77 | — | — | |
| SCHEMBL4386625 | 0.77 | — | — | |
| SCHEMBL4380984 | 0.77 | — | — | |
| SCHEMBL6427238 | 0.76 | TSHR (0.35) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407132-B1 | ANTIHISTAMINES, ANTIALLERGENS, ANTIASTHMATICS, ANTICONVULSANTS, AND ANTIDEPRESSANTS; SKIN RASH TREATMENT | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-06-18 | — | — | US | disclosed |