Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.68 |
| ▸ | CTSB | P07858 | 10/20 | 0.68 |
| ▸ | CTSS | P25774 | 9/20 | 0.68 |
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664683 | 1.00 | CTSL (0.68) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6738426 | 0.91 | CTSS (0.77) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6738423 | 0.91 | CTSS (0.77) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6840753 | 0.91 | CTSL (0.67) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6840750 | 0.91 | CTSL (0.67) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6737515 | 0.89 | CTSL (0.71) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6062072 | 0.89 | CTSB (0.71) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6737787 | 0.89 | CTSL (0.71) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6737510 | 0.89 | CTSL (0.71) | CTSLCTSBCTSSCTSKCTSV | |
| SCHEMBL6062083 | 0.89 | CTSB (0.71) | CTSLCTSBCTSSCTSKCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |