Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665171 | 1.00 | ABHD6 (0.32) | ABHD6DAGLAABCB1MMP12DAGLB | |
| SCHEMBL7449060 | 0.83 | HSD17B10 (0.34) | ABHD6DAGLAABCB1MMP12 | |
| SCHEMBL7458431 | 0.83 | HSD17B10 (0.34) | ABHD6DAGLAABCB1MMP12 | |
| SCHEMBL7451706 | 0.79 | ABCB1 (0.33) | ABHD6DAGLAABCB1DAGLB | |
| SCHEMBL7451704 | 0.79 | ABCB1 (0.33) | ABHD6DAGLAABCB1DAGLB | |
| SCHEMBL27496356 | 0.78 | ABCB1 (0.32) | ABHD6DAGLAABCB1 | |
| SCHEMBL7404865 | 0.76 | TMEM97 (0.31) | ABHD6DAGLA | |
| SCHEMBL27497033 | 0.75 | DRD4 (0.33) | — | |
| SCHEMBL7405602 | 0.75 | CTSL (0.31) | ABCB1MMP12 | |
| SCHEMBL7407015 | 0.75 | SMN1; SMN2 (0.33) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495699-B2 | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | AGOURON PHARMACEUTICALS INC. | 2002-12-17 | — | — | US | disclosed |