Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | PRKACG | P22612 | 2/20 | 0.41 |
| ▸ | PRKACB | P22694 | 2/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | PRKCB | P05771 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | PRKCH | P24723 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7665340 | 0.99 | ROCK1 (0.43) | ROCK1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL7671799 | 0.91 | HTR6 (0.40) | CYP3A4PMP22SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7671787 | 0.90 | HTR6 (0.40) | CYP3A4PMP22SMN1; SMN2 | |
| SCHEMBL7662944 | 0.84 | HRH3 (0.39) | CYP3A4LMNAPMP22F2MEN1 | |
| Hydrochloric Acid SCHEMBL7662933 | 0.83 | BLM (0.39) | CYP3A4LMNAPMP22F2MEN1 | |
| SCHEMBL9484225 | 0.82 | FLT3 (0.51) | ROCK1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL9484230 | 0.82 | FLT3 (0.51) | ROCK1PRKACAPRKACGPRKACBAKT2 | |
| SCHEMBL7672815 | 0.81 | OXTR (0.42) | CYP3A4LMNAPMP22MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7670137 | 0.79 | OXTR (0.41) | CYP3A4PMP22F2MEN1KMT2A | |
| SCHEMBL7663066 | 0.79 | PGR (0.41) | LMNAF2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |