Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350397 | 0.90 | HDAC1 (0.42) | ALOX15HDAC1HDAC10HDAC6KDM4A | |
| SCHEMBL7403265 | 0.89 | EPHX2 (0.49) | HDAC1HDAC10HDAC6KDM4ANAMPT | |
| SCHEMBL13385350 | 0.85 | EPHX2 (0.47) | HDAC1HDAC10HDAC6KDM4ANAMPT | |
| SCHEMBL6950153 | 0.84 | HDAC10 (0.43) | HDAC1HDAC10HDAC6KDM4ASLC7A5 | |
| SCHEMBL21987982 | 0.82 | IDO1 (0.51) | HDAC1HDAC10HDAC6KDM4AEPHX2 | |
| SCHEMBL29726461 | 0.82 | GRM2 (0.44) | HDAC1HDAC10HDAC6KDM4ANAMPT | |
| SCHEMBL15862086 | 0.81 | KDM4A (0.44) | ALOX15HDAC1HDAC10HDAC6KDM4A | |
| SCHEMBL7443631 | 0.80 | VCAM1 (0.44) | KDM4AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2062310 | 0.79 | ALOX15 (0.46) | ALOX15SLC7A5KDM4EALDH1A1GLA | |
| SCHEMBL1003573 | 0.79 | SLC7A5 (0.48) | ALOX15SLC7A5NR1H4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |