Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671498 | 0.85 | CA2 (0.44) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL3677249 | 0.83 | CA2 (0.43) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL1713465 | 0.82 | KIF11 (0.55) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL3675939 | 0.81 | CA2 (0.44) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL26549580 | 0.81 | KIF11 (0.71) | KIF11CA1CA2CA9 | |
| SCHEMBL3677375 | 0.80 | CA2 (0.46) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL3671119 | 0.78 | CA2 (0.47) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL24360466 | 0.77 | CA2 (0.62) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL5532552 | 0.77 | CA2 (0.62) | KIF11CA1CA2CA9CXCR2 | |
| SCHEMBL3673670 | 0.77 | KIF11 (0.50) | KIF11CA1CA2CA9CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |