SCHEMBL3671119

SCHEMBL3671119

O=S(=O)(Oc1ccc(C(F)(F)C(F)(F)c2ccc(Oc3ccc(C(F)(F)C(F)(F)c4ccc(OS(=O)(=O)C(F)(F)F)cc4)cc3)cc2)cc1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.47
CA1 P00915 5/20 0.47
CA9 Q16790 5/20 0.47
PTPN1 P18031 1/20 0.46
KIF11 P52732 1/20 0.43
CXCR2 P25025 2/20 0.41
CXCR1 P25024 1/20 0.40
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
AR P10275 1/20 0.36
ESR2 Q92731 1/20 0.36
SOS1 Q07889 2/20 0.36
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD4 P21917 1/20 0.36
DRD5 P21918 1/20 0.36
DRD3 P35462 1/20 0.36
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675939 0.93 CA2 (0.44) CA2CA1CA9PTPN1KIF11
SCHEMBL3671498 0.93 CA2 (0.44) CA2CA1CA9PTPN1KIF11
SCHEMBL3677249 0.91 CA2 (0.43) CA2CA1CA9PTPN1KIF11
SCHEMBL5179823 0.90 PTPN1 (0.53) CA2CA1CA9PTPN1KIF11
SCHEMBL3672358 0.85 PGR (0.45) CA2CA1CA9PTPN1KIF11
SCHEMBL3673670 0.84 KIF11 (0.50) CA2CA1CA9PTPN1KIF11
SCHEMBL576035 0.83 CA2 (0.50) CA2CA1CA9PTPN1KIF11
SCHEMBL3682645 0.83 CA2 (0.46) CA2CA1CA9PTPN1KIF11
SCHEMBL408478 0.82 CA1 (0.68) CA2CA1CA9KIF11CXCR2
SCHEMBL3671604 0.81 HTT (0.53) CA2CA1CA9PTPN1CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329444-B1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2010-05-05 EP disclosed
EP-1138712-B1 Polyarylene copolymers and proton-conductive membrane JSR CORP (JP) 2006-01-18 EP disclosed
US-6933068-B2 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2005-08-23 US disclosed
US-6833426-B2 A proton-conductive membrane containing the sulfonic acid group-containing polyarylene (co)polymer JSR CORPORATION (JP) 2004-12-21 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-6555626-B2 Controlled amount of sulfonic acid groups; copolymer of an aromatic compound having a main chain containing electron withdrawing groups and aromatic compounds with no electron withdrawing groups; durability, strength, conductivity JSR CORPORATION (JP) 2003-04-29 US disclosed
US-20020172850-A1 Polymer electrolyte membrane and solid polymer electrolyte fuel cell using same HONDA GIKEN KOGYO KABUSHIKI KAISHA, JSR CORPORATION 2002-11-21 US disclosed
US-20010037000-A1 Polyarylene copolymers and proton-conductive membrane JSR CORPORATION (JP) 2001-11-01 US disclosed
EP-1138712-A2 Polyarylene copolymers and proton-conductive membrane JSR Corporation (JP) 2001-10-04 EP disclosed