Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 4/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811570 | 0.87 | TDP1 (0.48) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL7078989 | 0.82 | GFER (0.58) | GFERMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7078992 | 0.76 | MEN1 (0.57) | GFERMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7785137 | 0.75 | MEN1 (0.44) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL6815687 | 0.74 | L3MBTL1 (0.53) | GFERMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7783875 | 0.73 | MAPT (0.56) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL3530485 | 0.73 | MAPT (0.62) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL7911933 | 0.73 | KMT2A (0.62) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL7078679 | 0.72 | FADS1 (0.55) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL6815137 | 0.71 | GFER (0.71) | GFERMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |