Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816255 | 0.88 | ALDH1A1 (0.66) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7785382 | 0.79 | KMT2A (0.63) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7079773 | 0.79 | KMT2A (0.69) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7567776 | 0.77 | MEN1 (0.50) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL5475142 | 0.74 | MEN1 (0.66) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7785213 | 0.73 | KMT2A (0.55) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7078679 | 0.73 | FADS1 (0.55) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7666015 | 0.73 | GFER (0.47) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7078989 | 0.72 | GFER (0.58) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7860654 | 0.72 | KMT2A (0.53) | KMT2AMEN1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |