SCHEMBL7666182

SCHEMBL7666182

CCOC(=O)C1CCOC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
ALDH1A1 P00352 4/20 0.42
PPM1B O75688 1/20 0.42
PTPN1 P18031 1/20 0.42
PPP1CC P36873 1/20 0.42
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LGMN Q99538 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301518 0.89 ALDH1A1 (0.47) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL72855 0.88 MAPT (0.51) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL20599646 0.86 SOAT1 (0.45) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL7660003 0.85 PPM1B (0.45) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL23780231 0.84
SCHEMBL4431630 0.82 SMN1; SMN2 (0.44) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL14961962 0.80 ADRB2 (0.38) ALDH1A1TSHR
SCHEMBL1869589 0.80 MAPT (0.43) MAPTALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL3692158 0.80 ADRB2 (0.33) PPM1BPTPN1PPP1CC
SCHEMBL1616230 0.79 MGAM (0.45) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362346-B1 HEATING MIXTURE OF FUROIC ACID WITH ACID CATALYST E. I. DU PONT DE NEMOURS AND COMPANY 2002-03-26 US disclosed