SCHEMBL7666190

SCHEMBL7666190

C=C(C)C(CO)S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9935951 0.82
SCHEMBL5595309 0.79 TGFBR1 (0.38) TGFBR1
SCHEMBL29077091 0.77 TP53 (0.32) TGFBR1TP53
SCHEMBL24817373 0.70 TGFBR1 (0.32) TGFBR1
SCHEMBL14435551 0.70 ALDH1A1 (0.37)
SCHEMBL3264628 0.69 OR51E2 (0.39) TGFBR1TP53
SCHEMBL9958231 0.67
SCHEMBL11272920 0.67 TSHR (0.33) TP53
SCHEMBL29110504 0.67 TDP1 (0.38) TP53
SCHEMBL9287871 0.65 RECQL (0.33) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500981-B1 REACTION PRODUCT OF 3,5-EPOXY-1-BUTENE AND SODIUM BISULFITE FOR PRODUCTION OF SELF DISPERSING AMPHOLYTE HOMO- AND COPOLYMERS FOR TREATMENT OF HAIR, SKIN, NAILS; PERMANENT ATNISTATICS ETHOX CHEMICALS LLC 2002-12-31 US disclosed