Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.64 |
| ▸ | CTSS | P25774 | 15/20 | 0.64 |
| ▸ | CTSK | P43235 | 8/20 | 0.64 |
| ▸ | CTSB | P07858 | 11/20 | 0.62 |
| ▸ | CTSV | O60911 | 6/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666326 | 1.00 | CTSL (0.64) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5529194 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5527598 | 0.82 | CTSL (0.73) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL6021768 | 0.79 | CTSL (1.00) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5517755 | 0.79 | CTSL (1.00) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5525751 | 0.79 | CTSL (0.71) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL5528277 | 0.78 | CTSL (0.83) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL23279751 | 0.78 | ACE (0.58) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL7594265 | 0.78 | CTSB (0.55) | CTSLCTSSCTSKCTSBCTSV | |
| SCHEMBL6184058 | 0.77 | CTSL (0.68) | CTSLCTSSCTSKCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |