Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965514 | 0.83 | XDH (0.47) | XDHAKR1B1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26174316 | 0.81 | XDH (0.53) | XDHALDH1A1KDM4EGDA | |
| SCHEMBL21183279 | 0.81 | XDH (0.44) | XDHALDH1A1KDM4EGDA | |
| SCHEMBL21258890 | 0.81 | XDH (0.41) | XDHALDH1A1SMN1; SMN2KDM4EGDA | |
| SCHEMBL766669 | 0.80 | XDH (0.66) | XDHGDA | |
| SCHEMBL2623143 | 0.79 | XDH (0.65) | XDHALDH1A1KDM4EKMT2A | |
| SCHEMBL5062459 | 0.78 | XDH (0.46) | XDHALDH1A1KDM4EKMT2AGDA | |
| SCHEMBL249648 | 0.78 | XDH (0.66) | XDHALDH1A1KDM4EKMT2A | |
| SCHEMBL8535455 | 0.77 | XDH (0.67) | XDHALDH1A1KDM4E | |
| SCHEMBL16205209 | 0.77 | XDH (0.50) | XDHALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11835499-B2 | Methods of quantifying methylglyoxal-induced nucleic acid adducts | CITY OF HOPE (US) | 2023-12-05 | — | — | US | disclosed |
| US-20220331273-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG | CITY OF HOPE (US) | 2022-10-20 | — | — | US | disclosed |
| US-11266618-B2 | Methods of quantifying N2-(1-carboxyethyl)-2′-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG | CITY OF HOPE (US) | 2022-03-08 | — | — | US | disclosed |
| US-11179361-B2 | Methods of quantifying N2-(1-carboxyethyl)-2′-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG | CITY OF HOPE (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200363381-A1 | METHODS OF QUANTIFYING METHYLGLYOXAL-INDUCED NUCLEIC ACID ADDUCTS | CITY OF HOPE (US) | 2020-11-19 | — | — | US | disclosed |
| WO-2019152728-A1 | METHODS OF QUANTIFYING METHYLGLYOXAL-INDUCED NUCLEIC ACID ADDUCTS | CITY OF HOPE (US) | 2019-08-08 | — | — | WO | disclosed |
| US-20180338939-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG | CITY OF HOPE | 2018-11-29 | — | — | US | disclosed |
| US-20180207116-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG | CITY OF HOPE | 2018-07-26 | — | — | US | disclosed |
| US-9855233-B2 | Methods of quantifying N2-(1-carboxyethyl)-2′-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG | CITY OF HOPE (US) | 2018-01-02 | — | — | US | disclosed |
| US-20150290156-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG | CITY OF HOPE | 2015-10-15 | — | — | US | disclosed |
| EP-2721046-A1 | METHODS FOR CHEMICAL SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS USING SUPRAMOLECULAR PROTECTIVE GROUPS AND NOVEL COMPOUNDS OBTAINABLE THEREBY | Rijksuniversiteit Groningen (NL) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012173477-A1 | METHODS FOR CHEMICAL SYNTHESIS OF BIOLOGICALLY ACTIVE COMPOUNDS USING SUPRAMOLECULAR PROTECTIVE GROUPS AND NOVEL COMPOUNDS OBTAINABLE THEREBY | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2012-12-20 | — | — | WO | disclosed |
| US-20120071559-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEdG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEdG | RAHBAR SAMUEL (US) | 2012-03-22 | — | — | US | disclosed |
| US-20100102218-A1 | METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEdG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEdG | CITY OF HOPE | 2010-04-29 | — | — | US | disclosed |