Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062047 | 0.75 | CTSS (0.36) | CTSSCTSBCTSL | |
| SCHEMBL4240318 | 0.72 | CTSL (0.33) | CTSSCTSBCTSL | |
| SCHEMBL7666715 | 0.70 | CTSS (0.44) | CTSSCTSBCTSLANO1 | |
| SCHEMBL6250638 | 0.66 | CNR1 (0.39) | CTSSCTSBCTSLANO1 | |
| SCHEMBL6255595 | 0.66 | CNR2 (0.35) | ANO1JAK2JAK1 | |
| SCHEMBL5438728 | 0.65 | CA12 (0.34) | — | |
| SCHEMBL6738439 | 0.64 | KDM4E (0.34) | — | |
| SCHEMBL6739784 | 0.64 | CTSS (0.46) | CTSSCTSBCTSL | |
| SCHEMBL4066120 | 0.64 | CTSL (0.37) | CTSSCTSBCTSL | |
| SCHEMBL4246964 | 0.63 | CTSL (0.37) | CTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |