Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | POLE3 | Q9NRF9 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683303 | 1.00 | MEN1 (0.47) | MEN1ALDH1A1KMT2ATGFBR1LMNA | |
| SCHEMBL30597491 | 0.83 | MEN1 (0.49) | MEN1ALDH1A1KMT2ATGFBR1LMNA | |
| SCHEMBL1244477 | 0.81 | MEN1 (0.47) | MEN1ALDH1A1KMT2ATGFBR1LMNA | |
| SCHEMBL21673038 | 0.81 | MEN1 (0.47) | MEN1ALDH1A1KMT2ATGFBR1LMNA | |
| SCHEMBL8330697 | 0.74 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ATGFBR1LMNA | |
| SCHEMBL20969207 | 0.73 | MEN1 (0.40) | MEN1ALDH1A1KMT2ATGFBR1NFE2L2 | |
| SCHEMBL7700637 | 0.73 | TSHR (0.40) | MEN1ALDH1A1KMT2ATGFBR1TSHR | |
| SCHEMBL20969489 | 0.72 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ATGFBR1TSHR | |
| SCHEMBL20969493 | 0.72 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ATGFBR1TSHR | |
| SCHEMBL32678441 | 0.71 | PTPN11 (0.36) | MEN1ALDH1A1KMT2APTPN11POLE3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384045-B1 | TREATMENT OF ALZHEIMER'S DISEASE AND ANTICANCER AGENTS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| US-5958970-A | ENZYME INHIBITORS OF ACETYLCHOLINESTERASE (ACHE) AND ACYL-COA:CHOLESTEROL ACYLTRANSFERASE (ACAT); USED IN THE TREATMENT OF ALZHEIMER'S DISEASE, ATHEROSCLEROSIS AND HYPERCHOLESTEROLEMIA | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1998039010-A1 | TRICYCLIC AND TETRACYCLIC PYRONES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1998-09-11 | — | — | WO | disclosed |