Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666649 | 0.86 | CHEK1 (0.39) | KDM4EPRMT5TNKS2BACE1CHEK1 | |
| SCHEMBL6776723 | 0.85 | AGTR1 (0.43) | KDM4EPRMT5TNKS2BACE1CHEK1 | |
| SCHEMBL7666760 | 0.83 | ALDH1A1 (0.43) | KDM4EPOLBPRMT5BACE1CHEK1 | |
| SCHEMBL7666815 | 0.77 | HPGD (0.44) | SMN1; SMN2HPGDMEN1KMT2ALMNA | |
| SCHEMBL12692930 | 0.75 | KDM4E (0.66) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7671424 | 0.75 | CCNC (0.42) | SMN1; SMN2CHEK1KMT2AGRIN1GRIN2B | |
| SCHEMBL7667782 | 0.73 | HPGD (0.43) | HPGDLMNA | |
| SCHEMBL6774478 | 0.71 | HPGD (0.49) | KDM4ESMN1; SMN2L3MBTL1HPGDLMNA | |
| SCHEMBL7665242 | 0.71 | HPGD (0.41) | SMN1; SMN2HPGDMEN1KMT2ALMNA | |
| SCHEMBL7671615 | 0.71 | HPGD (0.41) | KDM4ESMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |