Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.37 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046783 | 0.84 | OPRM1 (0.40) | MAPTALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL7665405 | 0.82 | ALDH1A1 (0.65) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7665411 | 0.82 | ALDH1A1 (0.65) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7667283 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL7667286 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL10440330 | 0.78 | OPRM1 (0.44) | L3MBTL1GAAEGLN1P2RX3DAGLA | |
| SCHEMBL10440329 | 0.77 | EGLN1 (0.41) | L3MBTL1GAAEGLN1P2RX3ATG4B | |
| SCHEMBL9046373 | 0.77 | ALDH1A1 (0.44) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL9044323 | 0.74 | LIPE (0.48) | MAPTALDH1A1HTTL3MBTL1LIPE | |
| SCHEMBL9044014 | 0.73 | GAA (0.39) | L3MBTL1GAAEGLN1P2RX3LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |