Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360395 | 0.84 | CD274 (0.59) | ESR2PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30496165 | 0.83 | ALDH1A1 (0.49) | ESR2ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL483697 | 0.83 | ALDH1A1 (0.49) | ESR2ALDH1A1MAPTSMN1; SMN2TSHR | |
| Bromide SCHEMBL4736034 | 0.81 | ALDH1A1 (0.47) | ESR2ALDH1A1MAPTSMN1; SMN2TSHR | |
| Fluoride SCHEMBL27645948 | 0.81 | ALDH1A1 (0.47) | ESR2ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL3181745 | 0.80 | DPP4 (0.52) | ESR2ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL27762059 | 0.80 | ESR2 (0.44) | ESR2PTPN5ALDH1A1PDE10ATSHR | |
| SCHEMBL588692 | 0.80 | ESR2 (0.44) | ESR2PTPN5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL222 | 0.80 | ESR2 (0.60) | ESR2PTPN5ALDH1A1TSHR | |
| SCHEMBL1221964 | 0.80 | PDCD1 (0.54) | PDCD1CD274TSHRAPOBEC3GBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195602-B | Symmetrical or semi-symmetrical compounds useful as immunomodulators | 上海齐鲁制药研究中心有限公司 | 2022-01-07 | — | — | CN | disclosed |
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |