Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496165 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| Fluoride SCHEMBL27645948 | 0.98 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| Bromide SCHEMBL4736034 | 0.98 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL7667378 | 0.83 | ESR2 (0.53) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL536176 | 0.82 | FFAR1 (0.44) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL30129807 | 0.82 | FFAR1 (0.44) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL1378624 | 0.80 | CA1 (0.41) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL28215006 | 0.80 | S1PR1 (0.40) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 | |
| SCHEMBL2154210 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2MAPTCYP19A1TSHR | |
| SCHEMBL2153612 | 0.80 | CYP19A1 (0.48) | ALDH1A1SMN1; SMN2MAPTCYP19A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572278-B | Genipin derivative and preparation method and application thereof | 北京志道生物科技有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-113816964-B | Reversible ionic liquid for capturing carbon dioxide and synthesis method thereof | 中国科学院兰州化学物理研究所 | 2023-02-10 | — | — | CN | claimed |
| CN-115572278-A | Genipin derivative and preparation method and application thereof | 北京志道生物科技有限公司 | 2023-01-06 | — | — | CN | claimed |
| WO-2022151968-A1 | METHOD FOR PURIFYING KEY INTERMEDIATES OF CITALOPRAM | 浙江华海药业股份有限公司 | 2022-07-21 | — | — | WO | claimed |
| CN-114488446-A | Optical cable cladding capable of being repeatedly used and preparation method thereof | 胡从美 | 2022-05-13 | — | — | CN | claimed |
| EP-3541791-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS | Rhodia Operations (FR) | 2019-09-25 | — | — | EP | claimed |
| EP-2978852-B1 | PRODUCTION OF PYRIPYROPENES FROM DRY BIOMASS | BASF SE (DE) | 2018-10-17 | — | — | EP | claimed |
| WO-2018085957-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS | RHODIA OPERATIONS (FR) | 2018-05-17 | — | — | WO | claimed |
| WO-2018086491-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS | RHODIA OPERATIONS (FR) | 2018-05-17 | — | — | WO | claimed |
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | claimed |
| US-20040259940-A1 | Process for the preparation of racemic citalopram and/or s-or r-citalopram by separation of a mixture of r-and s-citalopram | H. LUNDBECK A/S (DK) | 2004-12-23 | — | — | US | claimed |
| EP-1412341-B1 | PROCESS FOR THE PREPARATION OF RACEMIC CITALOPRAM AND/OR S- OR R-CITALOPRAM BY SEPARATION OF A MIXTURE OF R- AND S-CITALOPRAM | LUNDBECK & CO AS H (DK) | 2004-12-08 | — | — | EP | claimed |
| JP-2004536093-A | — | — | 2004-12-02 | — | — | JP | claimed |
| EP-1412341-A1 | PROCESS FOR THE PREPARATION OF RACEMIC CITALOPRAM AND/OR S- OR R-CITALOPRAM BY SEPARATION OF A MIXTURE OF R- AND S-CITALOPRAM | H. Lundbeck A/S (DK) | 2004-04-28 | — | — | EP | claimed |
| US-6576372-B1 | Hydroxy-containing substituent having a dipole moment is coupled to polyurethane through a NHCOO linkage | NISSHINBO INDUSTRIES, INC. (JP) | 2003-06-10 | — | — | US | claimed |
| WO-2003000672-A1 | PROCESS FOR THE PREPARATION OF RACEMIC CITALOPRAM AND/OR S- OR R-CITALOPRAM BY SEPARATION OF A MIXTURE OF R- AND S-CITALOPRAM | H. LUNDBECK A/S (DK) | 2003-01-03 | — | — | WO | claimed |
| EP-0132392-B1 | ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1992-01-02 | — | — | EP | claimed |
| US-4985365-A | WITH AN ESTERASE FROM A MICROORGANISM, ASSYMETRIC HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0347066-A1 | New enantiomers and their isolation | H. LUNDBECK A/S (DK) | 1989-12-20 | — | — | EP | claimed |
| EP-0132392-A2 | Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols | ICI AUSTRALIA LIMITED (AU) | 1985-01-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | ALDH1A1 3692/4885SMN1; SMN2 4595/4885MAPT 1768/4885 |
| US-20040259940-A1 | Process for the preparation of racemic citalopram and/or s-or r-citalopram by separation of a mixture of r-and s-citalopram | SLC6A4, SRR, SLC6A2 | ALDH1A1 1102/4885SMN1; SMN2 1432/4885MAPT 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.