SCHEMBL766864

SCHEMBL766864

CCCCCCCCCCc1cc(I)sc1I

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.41
ALOX5 P09917 5/20 0.41
TYR P14679 2/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LIPG Q9Y5X9 1/20 0.38
PTGS2 P35354 6/20 0.37
HTR2A P28223 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14485196 1.00 GPR35 (0.41) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL8974573 1.00 GPR35 (0.41) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL1422210 1.00 GPR35 (0.41) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL1422465 0.92 TYR (0.37) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL12730032 0.85 GPR35 (0.41) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL15412792 0.83 THRB (0.37) GPR35CYP3A4MEN1MAPTTSHR
SCHEMBL2855414 0.81 ALOX5 (0.39) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL2847059 0.81 ALOX5 (0.42) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL2855365 0.81 ALOX5 (0.42) GPR35ALOX5TYRCYP3A4MEN1
SCHEMBL2855161 0.81 GPR35 (0.39) GPR35ALOX5TYRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF UNIV MICHIGAN TECH (US) 2017-01-19 US disclosed
US-9412949-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2016-08-09 US disclosed
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2012-03-22 US disclosed
WO-2010075512-A1 POLYMERS WITH BODIPY-BASED BACKBONE FOR SOLAR CELLS MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2010-07-01 WO disclosed
WO-2010075514-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170014532-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 GPR35 2207/4885ALOX5 2164/4885TYR 2195/4885
US-20120070382-A1 FLUORESCENT CONJUGATED POLYMERS WITH A BODIPY-BASED BACKBONE AND USES THEREOF TLR3, TLR5, PARP15 GPR35 2207/4885ALOX5 2164/4885TYR 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.