Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675428 | 0.88 | LMNA (0.61) | LMNAALDH1A1THRBMAPTCA12 | |
| SCHEMBL7668449 | 0.80 | SMN1; SMN2 (0.58) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL7676013 | 0.78 | ALDH1A1 (0.50) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL7670219 | 0.78 | SMN1; SMN2 (0.48) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL7672988 | 0.77 | CA12 (0.49) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL7677540 | 0.77 | LMNA (0.50) | LMNAALDH1A1THRBMAPTCA12 | |
| SCHEMBL7674397 | 0.76 | KMT2A (0.46) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL6544478 | 0.76 | ALDH1A1 (0.53) | LMNAALDH1A1THRBMAPTCA12 | |
| SCHEMBL7672709 | 0.74 | LMNA (0.46) | LMNAALDH1A1MAPTCA12CA1 | |
| SCHEMBL7676614 | 0.73 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479550-B1 | α-sulfenimino acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2002-11-12 | — | — | US | claimed |