Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669034 | 1.00 | HDAC1 (0.53) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL30784638 | 0.95 | KDM4E (0.55) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13170362 | 0.77 | KDM4E (0.50) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13170482 | 0.77 | KDM4E (0.50) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28940691 | 0.75 | LTB4R (0.54) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL584596 | 0.73 | KDM4E (0.58) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL111230 | 0.73 | KDM4E (0.58) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL165795 | 0.72 | HDAC2 (0.75) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL165794 | 0.72 | HDAC2 (0.75) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL10747786 | 0.72 | HDAC1 (0.91) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420363-B1 | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |