Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.54 |
| ▸ | RXRB | P28702 | 9/20 | 0.54 |
| ▸ | RXRG | P48443 | 9/20 | 0.54 |
| ▸ | RARB | P10826 | 7/20 | 0.54 |
| ▸ | RARG | P13631 | 7/20 | 0.54 |
| ▸ | RARA | P10276 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880222 | 1.00 | RXRA (0.54) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6872171 | 0.87 | RARA (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6883867 | 0.84 | RARA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6878104 | 0.83 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7670810 | 0.83 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6878799 | 0.83 | GRM5 (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL2910172 | 0.83 | RARB (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6882358 | 0.83 | RARA (0.39) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9318320 | 0.82 | RXRA (0.58) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6882818 | 0.79 | RXRA (0.48) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441010-B2 | USEFUL AS COSMETIC FOR HAIR AND BODY HYGIENE, AND FOR TREATMENT OF DERMATOLOGICAL COMPLAINTS, WITH AN INFLAMMATORY AND/OR IMMUNOALLERGIC COMPONENT OF RHEUMATIC OR RESPIRATORY TYPE, CARDIVASCULAR AND OPTHALMOGICAL DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-08-27 | — | — | US | claimed |