Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662612 | 0.85 | LMNA (0.33) | LMNA | |
| SCHEMBL7666927 | 0.83 | LMNA (0.31) | LMNA | |
| SCHEMBL7698361 | 0.83 | LMNA (0.33) | LMNA | |
| SCHEMBL7664563 | 0.81 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL7665725 | 0.80 | NR3C2 (0.33) | LMNAALDH1A1 | |
| SCHEMBL7669454 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7665563 | 0.76 | CA12 (0.33) | ALDH1A1ALDH3A1 | |
| SCHEMBL7668786 | 0.72 | PTGS2 (0.34) | — | |
| SCHEMBL8498723 | 0.71 | LMNA (0.36) | LMNAALDH1A1 | |
| SCHEMBL7670184 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376540-B1 | PREVENT NEURODEGENERATIVE DISEASE | CENTAUR PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| US-6051571-A | NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-6040444-A | Process for preparing furan nitrone compounds | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5942507-A | REAGANTS FOR DETECTION FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-08-24 | — | — | US | disclosed |