Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5793684 | 0.98 | ALDH1A1 (0.69) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL8983360 | 0.91 | ALDH1A1 (0.69) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL30211332 | 0.88 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL2049483 | 0.88 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL19979736 | 0.88 | ALDH1A1 (0.65) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL212173 | 0.86 | ALDH1A1 (0.79) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL11547493 | 0.85 | KDM4E (0.66) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL18700963 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL31133329 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL7586167 | 0.85 | KDM4E (0.68) | ALDH1A1KMT2APTK2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
| CN-108003085-A | A kind of synthetic method of pharmaceutical intermediate sweet-smelling formacyl indole derivatives | 张开良 | 2018-05-08 | — | — | CN | disclosed |
| CN-106029654-A | Preparation of 3, 4-dihydro-1, 4-benzoxazepin-5 (2H) -one derivatives by cyclization of 2- (aminoethoxy) benzoic acid derivatives | 吉利德科学公司 | 2016-10-12 | — | — | CN | disclosed |
| US-6380185-B1 | FOR PREVENTION OF OSTEOPOROSIS, BONE LOSS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-1159268-A1 | N-SUBSTITUTED BENzOYL INDOLES AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051983-A1 | N-SUBSTITUTED BENzOYL INDOLES AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| US-5475021-A | Administering N-substituted succinimides | VANDERBILT UNIVERSITY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1995015163-A1 | NOVEL COMPOUNDS FOR INHIBITION OF CYCLOOXYGENASE ACTIVITY | VANDERBILT UNIVERSITY (US) | 1995-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | ALDH1A1 1721/4885KMT2A 4291/4885PTK2B 1112/4885 |
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | ILK, LRRC47, RPL37 | ALDH1A1 1721/4885KMT2A 4291/4885PTK2B 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.