SCHEMBL7669487

SCHEMBL7669487

CCN(CC)C(=O)n1ccnn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 4/20 0.40
PTBP1 P26599 1/20 0.38
P2RX1 P51575 1/20 0.38
P2RX3 P56373 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
P2RX7 Q99572 1/20 0.38
POLB P06746 3/20 0.37
BCHE P06276 1/20 0.37
ATM Q13315 1/20 0.37
HTR1A P08908 1/20 0.36
LMNA P02545 2/20 0.33
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
MGLL Q99685 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
HCRTR1 O43613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28323952 0.81 TACR1 (0.40) P2RX4P2RX1
SCHEMBL4971138 0.78 P2RX4 (0.35) P2RX4BCHEMGLL
SCHEMBL3583228 0.77
SCHEMBL14689260 0.74
SCHEMBL30666200 0.73 SMN1; SMN2 (0.36) SMN1; SMN2NPSR1POLBATMTDP1
SCHEMBL876240 0.72
SCHEMBL1428148 0.72 FAAH (0.31)
SCHEMBL166053 0.71 FOLH1 (0.32)
SCHEMBL29299953 0.71 NOTUM (0.33)
SCHEMBL2569453 0.71 CES1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND THE UNIVERSITY OF TOKYO (JP) 2023-01-26 US disclosed
US-6461997-B1 SUCH AS 3-(BROMODIFLUOROMETHYLSULFONYL)-1-(N,N-DIETHYL-CARBAMOYL)-1,2,4-TRIAZOLE; SELECTIVITY FOR WEEDS OVER CROPS; APPLY TO PLANTS OR SOIL MONSANTO TECHNOLOGY LLC 2002-10-08 US disclosed
EP-1140865-A1 TRIAZOLE SULFONES HAVING HERBIDICIDAL ACTIVITY Monsanto Co. (US) 2001-10-10 EP disclosed
WO-2000042028-A1 TRIAZOLE SULFONES HAVING HERBICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2000-07-20 WO disclosed
EP-0126326-B1 PROCESS FOR PREPARING 1,2,4-TRIAZOLE-3-CARBOXAMIDES UBE INDUSTRIES, LTD. (JP) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024778-A1 STRIGOLACTONE RECEPTOR INHIBITOR, AGRICULTURAL COMPOSITION AND USE THEREOF, STRIGA SEED GERMINATION INHIBITOR, AND TRIAZOLE UREA COMPOUND UTS2R, TAS1R1, ULK3 P2RX4 2150/4885PTBP1 4412/4885P2RX1 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.